姓名：王妍性別：女政治面貌：中共黨員學(xué)歷：研究生學(xué)位：博士職稱：講師
博,、碩導(dǎo)師：碩導(dǎo)本崗位工作年數(shù)：4年
研究方向：移植免疫、腫瘤免疫,、感染免疫
榮譽(yù)稱號：山西醫(yī)科大學(xué)2023-2024年度“青年五四獎(jiǎng)?wù)隆?/p>
山西醫(yī)科大學(xué)第一醫(yī)院“優(yōu)秀共產(chǎn)黨員”（2023年）
學(xué)術(shù)任職：無
近五年承擔(dān)科研課題情況：
1.國家自然科學(xué)基金委員會,青年科學(xué)基金項(xiàng)目,項(xiàng)目名稱：PRAK通過NEDD4L-PAD4調(diào)控系統(tǒng)性紅斑狼瘡中中性粒細(xì)胞胞外誘捕網(wǎng)形成的機(jī)制研究,項(xiàng)目編號:32200717
2.山西省基礎(chǔ)研究計(jì)劃（自由探索類）青年項(xiàng)目,，項(xiàng)目名稱：PRAK介導(dǎo)的氧化應(yīng)激反應(yīng)對Th17細(xì)胞分化的調(diào)節(jié)在肝細(xì)胞癌中的作用，項(xiàng)目編號：2021002124092
代表性論著及近五年的代表性論文（限10項(xiàng)以內(nèi)）：
1. Zhao Ziheng#,Wang Yan#, Gao Yuhan, Ju Yurong, Zhao Ye, Wu Zhaofei, Gao Shuaixin , Zhang Boyang, Pang Xuewen, Zhang Yu, and Wang Wei; The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis, Proc Natl Acad Sci U S A. 2023, 120(19): e2212613120
2.Wang Yan, Wang Yuqing, Wu Jia, Liu Chen, Zhou Yu, Mi Ligu, Zhang Yu, Wang Wei; PRAK Is Required for the Formation of Neutrophil Extracellular Traps, Frontiers in Immunology, 2019, 10: 1252
3. Li Manyu#,Wang Yan#, Li Kejian, Lan Haiyun and Zhou Cheng,；Characterization of highly expressed novel hub genes in hepatitis E virus chronicity in rabbits: abioinformatics and experimental analysis,，BMC Veterinary Research，2022,18:239
4. Li Xinqiang#, Li Shipeng#,Wang Yan, Zhou Xin, Wang Feng, Muhammad Imran, Luo Yurong, Sun Yandong, Liu Dan, Wu Bin, Teng Dahong, Wang Jinshan, Zhao Kai, Ling Qi, Cai Jinzhen; Single cell RNA-sequencing delineates CD8+ tissue resident memory T cells maintaining rejection in liver transplantation, THERANOSTICS, 2024, 14(12): 4844-4860
5. Wang Yuqing#, Wang Wei#, Wu Haoming, Zhou Yu, Qin Xiaodan,Wang Yan, Wu Jia, Sun Xiuyuan, Yang Yan, Xu Hui, Qian Xiaoping, Pang Xuewen, Li Yan, Zhang Zhiqian, Han Hiahuai, Zhang, Yu; The essential role of PRAK in tumor metastasis and its therapeutic potential, Nature Communications, 2021, 12(1): 1736
6. Zhou Xiao Albert#, Zhou Jiadong#, Zhao Long, Yu Guihui, Zhan Jun, Shi Chanyi, Yuan Ruoshi,Wang Yan, Chen Changfeng, Zhang Wenjia, Xu Donghao, Ye Yingjiang, Wang Weibin, Shen Zhanlong*, Wang Wei*, Wang Jiadong* ; KLHL22 maintains PD-1 homeostasis and prevents excessive T cell suppression, Proceedings of the National Academy of Sciences of the United States of America,2020, 117(45): 2839-2850
7. Mi Ligu,Wang Yan, Xu Hui, Wang Yu, Wu Jia, Dai Hui*, Zhang Yu*; PRAK Promotes the Pathogen Clearance by Macrophage Through Regulating Autophagy and Inflammasome Activation, Frontiers in Immunology, 2021, 12: 618561
教學(xué)科研
