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導(dǎo)師簡(jiǎn)介

姓名：楊海瀾性別：女政治面貌：中共黨員學(xué)歷：博士學(xué)位：博士職稱(chēng)：主任醫(yī)師

博、碩導(dǎo)師：博導(dǎo)本崗位工作年數(shù)：37

研究方向：包括妊娠期高血壓,、妊娠期糖尿病,、宮頸機(jī)能不全及胎盤(pán)植入等疾病的發(fā)病機(jī)制及細(xì)胞替代治療策略探索、常見(jiàn)妊娠期動(dòng)物模型的建立及應(yīng)用,。

榮譽(yù)稱(chēng)號(hào)：省級(jí)高級(jí)訪(fǎng)問(wèn)學(xué)者,，獲省部級(jí)科技進(jìn)步獎(jiǎng)3項(xiàng)，其中,，山西省科技進(jìn)步三等獎(jiǎng)一項(xiàng),，山西省科技進(jìn)步二等獎(jiǎng)兩項(xiàng)。榮獲“國(guó)務(wù)院政府特殊津貼”,，“婦幼健康突出貢獻(xiàn)榮譽(yù)獎(jiǎng)”,，山西省“三晉英才”，山西省“三八紅旗手”,、“山西最美婦幼天使”榮譽(yù)稱(chēng)號(hào),，校級(jí)教學(xué)能手。

學(xué)術(shù)任職：現(xiàn)兼任中華醫(yī)學(xué)會(huì)圍產(chǎn)醫(yī)學(xué)分會(huì)常務(wù)委員,，中國(guó)婦幼保健協(xié)會(huì)促進(jìn)自然分娩專(zhuān)業(yè)委員會(huì)名譽(yù)主任委員,，山西省女醫(yī)師協(xié)會(huì)圍產(chǎn)醫(yī)學(xué)專(zhuān)業(yè)委員會(huì)主任委員，山西省婦幼保健協(xié)會(huì)圍產(chǎn)保健及促進(jìn)自然分娩專(zhuān)家委員會(huì)主任委員,，山西省健康管理學(xué)會(huì)婦產(chǎn)科管理專(zhuān)業(yè)副主任委員,，山西省女醫(yī)師協(xié)會(huì)婦產(chǎn)科專(zhuān)業(yè)副主任委員,，山西省醫(yī)學(xué)會(huì)圍產(chǎn)醫(yī)學(xué)專(zhuān)業(yè)委員會(huì)副主任委員等。

近五年承擔(dān)科研課題情況：

(1)山西省科技廳（自由探索類(lèi)）,項(xiàng)目名稱(chēng)：臍帶間充干細(xì)胞調(diào)控滋養(yǎng)細(xì)胞自噬在改善子癇前期中的作用和機(jī)制研究,項(xiàng)目編號(hào)：202403021211165.

(2)山西省中醫(yī)藥管理局（傳承創(chuàng)新）,項(xiàng)目名稱(chēng)：山西省子癇前期篩查質(zhì)量控制系統(tǒng)聯(lián)合中醫(yī)藥防治研究項(xiàng)目,項(xiàng)目編號(hào)：2024ZYYA016.

(3)山西省衛(wèi)健委（科技創(chuàng)新基地建設(shè)）,項(xiàng)目名稱(chēng)：妊娠期嚴(yán)重并發(fā)癥間充質(zhì)干細(xì)胞療法創(chuàng)新,項(xiàng)目編號(hào)：YDZJSX2022B010.

(4)山西省衛(wèi)健委（國(guó)家臨床重點(diǎn)專(zhuān)科建設(shè)）,項(xiàng)目名稱(chēng)：源于臍帶組織干細(xì)胞庫(kù)建立及質(zhì)量評(píng)價(jià)體系構(gòu)建,，項(xiàng)目編號(hào)：Y2022ZD001.

代表性論著及近五年的代表性論文（限10項(xiàng)以?xún)?nèi)）：

(1) Liang, Yuxiang; Meng, Jian; Yu, Zhaowei; Guo, Yuqian; Zhang, Xiao; Yan, Yujia; Du, Shaobo; Jin, Shanshan; Li, Jing; Hailan Yang; Zhang, Xiaozheng; Liu, Zhizhen; Li, Liping; Xie, Jun ; Ru single-atom nanozymes targeting ROS-ferroptosis pathways for enhanced endometrial regeneration in intrauterine adhesion therapy, BIOMATERIALS, 2025, 315: 122923-122923.

(2) Yinmin Chen; Zhuanzhuan Gao; Liyuan Wang; Ruiyun Duan; Huiniu Hao; Ran Jia; Huijing Ma; Ruifan Gao; Min Su; Hailan Yang; Zengrong Tu; The effects of metformin on inflammation and apoptosis in rats with preeclampsia, Journal of Hypertension, 2024, 42(1): 1-1.

(3) Hao H, Li F, Wang F, Ran J, Chen Y, Yang L, Ma H, Wang J, Yang H. Protective effect of metformin on the NG-nitro-l-arginine methyl ester (l-NAME)-induced rat models of preeclampsia. Biochem Biophys Res Commun. 2024 Dec 20;739:150996.

(4) Jia, Ran; Ma, Huijing; Hao, Huiniu; Wang, Fang; Hailan Yang; Metformin inhibits activation of NLRP3 inflammasome and inflammatory response in preeclamptic rats, GENE, 2024, 919: 148509.

(5) Lijun Deng; Beibei Ning; Hailan Yang; Association between gestational diabetes mellitus and adverse obstetric outcomes among women with advanced maternal age A retrospective cohort study, Medicine (Baltimore), 2022, 40(101): e30588.

(6) Jianli Wang; Hailan Yang; Effect of carboprost tromethamine injection combined with modified B-lynch suture and carboprost methylate suppositories in parturients with placenta previa, American Journal of Translational Research, 2021, 7(13): 7812-7818.

(7) Mengnan Li; Min Hu; Zhijing Yue; Yudan Zhang; Hailan Yang; The interactive effects of non-alcoholic fatty liver disease and hemoglobin concentration in the first trimester on the development of gestational diabetes mellitus, PLOS ONE, 2021, 9(16): e0257391.

(8) Yu Han; Hailan Yang ; The transmission and diagnosis of 2019 novel coronavirus infection disease (COVID‐19): A Chinese perspective, Journal of Medical Virology, 2020, 92: 639-644.

(9) Yu Han; Mengnan Li; Huijing Ma; Hailan Yang; Cervical insufficiency: a noteworthy disease with controversies, Journal of perinatal medicine, 2020, 48(7): 648-655.

(10)主編.健康人文：圍產(chǎn)期關(guān)懷篇[M].北京：人民衛(wèi)生出版社,，2018.3 ISBN 978-7-117-25940-8/R·25941.